What impact will China have on future pandemics? Credit: STR/AFP via Getty

Just over a year ago, I stumbled across an intriguing scientific paper. It suggested the pandemic that was ripping around the world was “uniquely adapted to infect humans”; it was “not typical of a normal zoonotic infection” since it first appeared with “exceptional” ability to enter human cells. The author of the paper, Nikolai Petrovsky, was frank about the disease when we spoke back then, saying its adaptability was either “a remarkable coincidence or a sign of human intervention”. He even broke the scientific omertà by daring to admit that “no one can say a laboratory leak is not a possibility”.
But even though Petrovsky has excellent credentials — professor of medicine at a prominent Australian university, author of more than 200 papers in scientific journals and founder of a company funded by the US government to develop new vaccine technologies — I was still anxious when my story went global. His original document had been posted on a pre-print site, so had not been peer reviewed, unlike if it had been published in a medical or scientific journal. These sorts of sites allow researchers to get findings out quickly. Petrovsky told me his first attempt to place these seismic findings was on BioRxiv, run by prominent New York laboratory. But it was rejected; eventually he succeeded on ArXiv, a rival server run by Cornell University. Last week, however, he told me this important origins modelling paper had finally been accepted by Nature Scientific Reports after “a harrowing 12 months of repeated reviews, rejections, appeals, re-reviews and finally now acceptance”.
This acceptance is one more sign of the changing political climate as suddenly it is deemed permissible to discuss the possibility that the virus causing havoc around the world might have emerged from a laboratory. Petrovsky has had to endure what he calls “the legitimacy” of his paper as a peer-reviewed publication being denied for a critical 12 months — and he is far from alone. “I have heard all too many tales from other academics who have been equally frustrated in getting their manuscripts dealing with research into the origins of the virus published,” he said.
Bear in mind that in the heat of this pandemic, papers printed in important journals were peer-reviewed within 10 weeks; one rattled through the process in just nine days for Nature. But, like Petrovsky, I have heard similar stories from many other frustrated experts who confronted the conventional wisdom that this lethal virus was a natural spillover event. Some could not even get letters published, let alone challenge those key papers promoting the Chinese perspective which have since turned out to be flawed or wrong.
Only now is acceptance emerging that the science establishment colluded to dismiss the lab leak hypothesis as a conspiracy theory, assisted by prominent experts with clear conflicts of interest, patsy politicians and a pathetic media that mostly failed to do its job. And yet, at the heart of this scandal lie some of the world’s most influential science journals. These should provide a forum for pulsating debate as experts explore and test theories, especially on something as contentious and fascinating as the possible origins of a global pandemic. Instead, some have played a central role in shutting down discussion and discrediting alternative views on the origins, with disastrous consequences for our understanding of events.
Many scientists have been dismayed by their actions. “It is very important to talk about the scientific journals — I think they are partially responsible for the cover-up,” said Virginie Courtier-Orgogozo, a leading French evolutionary biologist and key member of the Paris Group of scientists challenging the established view on these issues. The rejection of the lab leak hypothesis, she argues, in many places was not due to Trump’s intervention but the result of “respectable scientific journals not accepting to discuss the matter”.
The Paris Group, for instance, submitted a letter to The Lancet in early January signed by 14 experts from around the world calling for an open debate, arguing that “the natural origin is not supported by conclusive arguments and that a lab origin cannot be formally discarded”. This does not seem contentious. But it was rejected on the basis it was “not a priority for us”. When the authors queried this decision, it was reassessed and returned without peer review by editor-in-chief Richard Horton with a terse dismissal saying “we have agreed to uphold our original decision to let this go”. The authors ended up publishing their statement on a pre-print site.
Yet this is the same prestigious journal that published a now infamous statement early last year attacking “conspiracy theories suggesting that Covid-19 does not have a natural origin“. Clearly, this was designed to stifle debate. It was signed by 27 experts but later turned out to have been covertly drafted by Peter Daszak, the British scientist with extensive ties to Wuhan Institute of Virology. To make matters worse, The Lancet then set up a commission on the origins — and incredibly, picked Daszak to chair its 12-person task force, joined by five others who signed that statement dismissing ideas the virus was not a natural occurrence.
Horton has been scathing about British government failures on the pandemic, even publishing a book lambasting them. Perhaps he would do well to turn his critical fire on his own journal’s failings as its 200th anniversary approaches. This is, remember, the same organ that inflamed the anti-vaccine movement by promoting Andrew Wakefield’s nonsense on MMR jabs — and then took 12 years to retract the damaging paper. But it is far from alone. The Paris Group has been collecting details of dissenting scientists, whose letters or critical articles were rebuffed by key journals which include Nature and Science, another two of the world’s most influential vehicles for scientific debate.
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